1rst International Symposium of the CNRS International Research Network CeSMeR

9:00 - 10:10 (1h10)

Thème 2 : Interactions cellules/scaffold et cellules/environnement

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

› Optimization of stem cell properties by Heparan sulfate mimetics : towards new therapeutic strategies for the treatment of osteoarthritis. - Patricia ALBANESE, Gly-CRRET Laboratory, Glycobiology, Growth, Repair, and Tissue Regeneration (GlyCRRET), EA 4397, 09:00-09:30 (30min)

› CHEMICAL, PHYSICAL AND BIOLOGICAL STRATEGIES TO MODIFY CELLULOSE/ SOY PROTEIN COMPOSITES-BASED NERVE CONDUITS FOR PERIPHERAL NERVE REGENERATION - Y. Chen, School of Basic Medical Sciences, Wuhan University 09:30-10:00 (30min)

10:00 - 10:10 (10min)

Explore Agilent cell analysis technologies to gain deeper insight into stem cell function and uncover mechanisms involved in cellular reprogramming and differentiation

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

C. IOCHEM - Agilent Technologies

10:10 - 11:15 (1h05)

Pause café & Posters

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

11:15 - 12:15 (1h)

Thème 2 : Interactions cellules/scaffold et cellules/environnement

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

› HYPOXIA PRECONDITIONING IMPROVES QUALITY OF MESENCHYMAL STEM CELLS AND ENPOWERS THEIR IMMUNOREGULATORY POTENTIAL - Yinping Li, School of Basic Medical Sciences, Wuhan University 11:15-11:30 (15min)

› DEVELOPMENT OF A MECHANICAL BIOPROCESS TO STIMULATE STEM CELLS FOR REGENERATIVE MEDECINE - Emilie Wiedemann-Fodé, Laboratoire d'Etude des Microstructures et de Mécanique des Matériaux 11:30-11:45 (15min)

› CHARACTERIZATION OF SMALL SIZE EXTRACELLULAR VESICLES FROM WHARTON'S JELLY MESENCHYMAL STEM CELLS DURING IN VITRO EXPANSION AND STUDY OF CXCR4 EXPRESSION - Stéphane BREZILLON, 1Université de Reims Champagne-Ardenne, UMR CNRS, 7369 MEDyC, Reims, France 11:45-12:00 (15min)

› NEUROTOXIC A1 ASTROCYTES PROMOTE NEURONAL FERROPTOSIS IN EPILEPSY - Song Han, School of Basic Medical Sciences, Wuhan University, Wuhan, Hubei Provincial Key Laboratory of Developmentally Originated Disease, Taikang Medical School, School of Basic Medical Sciences, Wuhan University, Wuhan, China 12:00-12:15 (15min)

12:15 - 14:00 (1h45)

Déjeuner

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

14:00 - 15:10 (1h10)

Thème 3 : Ingénierie cellulaire

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

› Bringing Mesenchymal stromal cells into the clinic - Nadir Kadri, Department of Laboratory Medicine 14:00-14:30 (30min)

› Use of MAIT cells as a new platform for universal CAR-expressing cells. - Sophie Caillat-Zucman, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Université de Paris, Laboratoire d'Immunologie 14:30-15:00 (30min)

15:00 - 15:10 (10min)

Umbilical Cord Stem Cells for Cell Therapy & Regenerative Medicine

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

P. SQUIBAN - Health & Biotech France

15:10 - 16:15 (1h05)

Pause café & Posters

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

16:15 - 17:15 (1h)

Thème 3 : Ingénierie cellulaire

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

› DELIVERING LINE1 ANTISENSE OLIGONUCLEOTIDES VIA ENDOTHELIAL TARGETING EXTRACELLULAR VESICLES TO AMELIORATE MYOCARDIAL INFARCTION-INDUCED CARDIAC SENESCENCE - Zongjin Li, School of Medicine, Nankai University, Henan Key Laboratory of Cardiac Remodeling and Transplantation, Zhengzhou Seventh People's Hospital, Zhengzhou 450016, China 16:15-16:30 (15min)

› CAR-VST as a promising candidate to produce allogeneic CAR-T cells - Valentine Wang, IMoPA 16:30-16:45 (15min)

› Effect of the oxygenation on the growth of human wharton's jelly-mesenchymal stromal cells and extracellular vesicles production in mixed bioreactors - Kevin Audoux, Laboratoire Réactions et Génie des Procédés 16:45-17:00 (15min)

› EXAMPLE OF IMPROVEMENT OF THE ANTITUMOR POTENTIAL OF NATURAL KILLER CELLS WITHOUT GENE MODIFICATION: ARMING NK CELLS AGAINST MEDULLOBLASTOMA WITH ANTI-HER ANTIBODIES. - Mélanie GAUTHIER, Ingénierie Moléculaire, Cellulaire et Physiopathologie, Unité de Thérapie Cellulaire : CHRU Nancy - Veronique Decot, Ingénierie Moléculaire, Cellulaire et Physiopathologie, Unité de Thérapie Cellulaire : CHRU Nancy 17:00-17:15 (15min)

17:15 - 18:00 (45min)

Sessions de clôture / Prix

Amphithéâtre LEPOIS – Faculté de Médecine, Maïeutique et Métiers de la Santé

Pr C. Huselstein, University of Lorraine, CNRS, UMR 7365

Programme